Dr. Lars Svensson, Chairman of the Heart and Vascular Institute and Dr. Samir Kapadia, Section Head, Interventional Cardiology have been involved with PARTNER trials over many years. Together, they discuss the history of the PARTNER Transcatheter aortic valve replacement (TAVR) trials, the results of the low risk PARTNER 3 trial and its impact on patient care, additional trials of interest such as the TAVR UNLOAD trial for heart failure patients and EARLY TAVR for asymptomatic AS. Transcatheter aortic valve replacement - https://my.clevelandclinic.org/health/treatments/17570-transcatheter-aortic-valve-replacement-tavr Dr. Lars Svensson - https://my.clevelandclinic.org/staff/4359-lars-svensson Dr. Samir Kapadia - https://my.clevelandclinic.org/staff/5003-samir-kapadia