Contemporary Strategies: Diagnosing ATTR Amyloidosis

Agenda

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• Moderator Introduction: Mazen Hanna, MD
• Case Presentation: Jeremy Brooksbank, MD
• Overview of ATTR Amyloidosis – Pathophysiology & Types: Mazen Hanna, MD
• Imaging Modalities to Make the Diagnosis
• MRI in Aortic Stenosis – Assessment of Amyloidosis: Deborah Kwon, MD
• PYP Scan: Aortic Stenosis – Added Cost or Not: Bryan Abadie, MD
• Diagnostic Considerations 
• Heart Failure Perspective: Andres Carmona Rubio, MD
• Oncology Perspective: Jason Valent, MD
• Overview of Future Amyloid Sessions: Mazen Hanna, MD

Learning Objectives:

• Identify common diagnostic issues for patients with ATTR.
• Recognize ATTR genotypes and phenotypes, including typical symptomatology.
• Discuss multidisciplinary strategies for confirming ATTR diagnosis.

Complete CME process to claim your credit.

Learn More about the Cleveland Clinic Amyloidosis Center.

Target Audience
This online series is designed for physicians, allied health practitioners and students interested in complex cardiovascular and thoracic conditions.

Accreditation
In support of improving patient care, Cleveland Clinic Center for Continuing Education is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

Credit Designation American Medical Association (AMA)
Cleveland Clinic Center for Continuing Education designates this enduring activity for a maximum of 1.0 AMA PRA Category 1 CreditTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Participants claiming CME credit from this activity may submit the credit hours to the American Osteopathic Association for Category 2 credit.

Certificate of Participation
A certificate of participation will be provided to other health care professionals for requesting credits in accordance with their professional boards and/or associations.

CME Disclaimer
The information in this educational activity is provided for general medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient's medical condition. The viewpoints expressed in this CME activity are those of the authors/faculty. They do not represent an endorsement by The Cleveland Clinic. In no event will The Cleveland Clinic be liable for any decision made or action taken in reliance upon the information provided through this CME activity.

Faculty Disclosure
In accordance with the Standards for Commercial Support issued by the Accreditation Council for Continuing Medical Education (ACCME), The Cleveland Clinic Center for Continuing Education requires resolution of all faculty conflicts of interest to ensure CME activities are Free of commercial bias.

The following faculty has indicated they have no relationship which, in the context of their presentation(s), could be perceived as a potential conflict of interest: Kathleen Breznai, Bryan Abadie, MD, Andres E Carmona Rubio, MD, Deborah H Kwon, MD.

The following faculty has indicated that they may have a relationship, which in the context of their presentation(s) could be perceived as a potential conflict of interest: Eric E Roselli, MD, Activity Director: Cook Medical - Teaching and Speaking. Cryolife, Inc. - Consulting. Terumo - Teaching and Speaking. W.L. Gore & Associates - Consulting. Medtronic - Consulting. Edwards Lifesciences - Teaching and Speaking. Abbott - Teaching and Speaking. LivaNova, PLC - Consulting, Teaching and Speaking. Michael Tong, MD: Abiomed - Consulting, Teaching and Speaking. Abbott - Consulting, Teaching and Speaking.Mazen Hanna, MD: Pfizer - Advisor or review panel participant. Alexion - Advisor or review panel participant. Alexion - Advisor or review panel participant. Alnylam - Advisor or review panel participant. Akcea Therapeutics, Inc. - Advisor or review panel
participant. Eidos Therapeutics - Advisor or review panel participant.

The Cleveland Clinic Center for Continuing Education acknowledges educational grants for partial support of this activity from:

• Alexion Pharmaceuticals, Inc.
• Alnylam Pharmaceuticals, Inc.
• AstraZeneca Pharmaceuticals

For further information about this activity, contact Katie Breznai at breznak@ccf.org